The device for lipo-reductive purposes has been specifically designed to prevent unwanted tissue injury. The ultrasound emitter, was demonstrated to achieve selective adipocyte lysis and clinically relevant reduction of the volume of subcutaneous fat pad, in the absence of significant adverse reactions. It has been shown that adipose cell cavitation induces focal alterations of the plasma membrane and lipid leakage. Anesthesia is not necessary prior to the use of the cavitation ultrasound machine. This simple procedure for fat reduction can be done within the clinic and results are typically seen immediately. It is suggested to periodically maintain these treatments in order to see the best results. Various clinical studies further strengthens the current notion that noninvasive trans-cutaneous ultrasound cavitation is a promising and safe technology for localized reduction of fat and provides evidence for its specific mechanism of action on the adipocytes.